Tuberculosis

Ending Tuberculosis—Where Urgent Innovation, Access and Social Change Meet

Tuberculosis (TB) remains the world’s deadliest infectious disease, with 10.8 million people affected in 2023—driven by poverty, undernutrition, crowded conditions, HIV, and other social determinants. At this critical moment, Jhpiego is accelerating action to end TB as a global threat by 2030 collaborating closely with ministries of health, national health systems, and social protection systems including the private sector, civil society, and local communities.

We support high-burden countries to expand access to timely diagnosis, treatment, and prevention for those most at risk through targeted active case finding, vulnerability mapping, and innovative screening methods such as AI-powered cough analysis and advanced digital tools. We explore emerging point-of-care diagnostics and non-sputum-based tests. Working together, we strengthen differentiated TB care models that substantially reduce mortality and advance integrated, community-driven approaches. These include social protection community-driven models, robust primary health care, and services related to maternal and child health, HIV, mental health, and post-TB lung care. By tackling the social and structural drivers of TB, countries and communities are transforming urgency into lasting impact for all.

OUR APPROACHES

Strong Partnerships

  • We work closely with ministries of health, civil society, local organizations, and communities to strengthen national TB responses and tailor solutions to local needs.

Person-centered, integrated care

  • We help governments and partners deliver TB services by integrating prevention, diagnosis, and treatment into HIV, primary health care, and maternal and child health programs.

Health workforce strengthening

  • We help build capacity across the health workforce—from clinical mentors and instructors to nursing students—to ensure delivery of high-quality TB and HIV services.

Innovative service delivery

  • We optimize TB care and treatment through differentiated models of care, community outreach, and “one-stop shops” to expand access, reduce barriers to care, and improve case findings and treatment adherence among people living with HIV.

Evidence-based innovations

  • We support the rollout of proven tools like the 12-week high-dose isoniazid and rifapentine 3HP regimen to treat latent TB infections.

Program Experts

Dr. Silvia Kelbert

Principal Technical Advisor for Tuberculosis

Tuberculosis: An Overlooked Threat to Pregnant Women

Tuberculosis is the world’s deadliest infectious disease, and a hidden threat to pregnant women. In countries like Lesotho, where TB and maternal deaths intersect, failure to act costs lives. Discover why integrated, person-centered care is essential to ending TB.

“Ending TB is not a question. It is a must. But it requires thinking and working differently. If we as a global community are serious about ending TB, we need embrace new ways to accelerate innovation and equitable access to treatment, prevention and social support for people affected by TB and their communities.”
— Dr. Silvia Kelbert, Senior Technical Advisor for Jhpiego