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Saving lives through the control of the HIV epidemic and strengthening global health security

The Reaching Impact Saturation and Epidemic Control (RISE) program is saving lives and improving health by controlling the HIV pandemic and strengthening global health security to limit the spread of deadly disease outbreaks. RISE uses evidence-based practices from over 20 years of global health service delivery to address critical HIV and global health security priorities. As of September 2024, RISE support ensured: Almost 4,000,000 people— including 931,000 pregnant women—were tested for HIV and about 150,000 people accessed lifesaving antiretroviral treatment (ART), suppressing the virus in about 95% of clients; nearly 14,000 infants underwent early infant HIV diagnosis; over 75,000 health workers were trained in emergency and critical care; and 30,000 health workers were trained to prevent and control the spread of infection in health facilities.

KEY RESOURCES

About RISE

Providing lifesaving services in more than 25 countries.

RISE is saving lives and improving health by controlling the HIV pandemic and strengthening global health security to limit the spread of deadly disease outbreaks. Across more than 25 countries, RISE uses evidence-based practices from over 20 years of PEPFAR implementation to address critical HIV and global health security priorities. RISE is also able to support maternal, newborn, and child health (MNCH), tuberculosis (TB), and malaria programming, along with support for data systems, supply chain and commodity management, and other crosscutting areas. Read more.

HIV Epidemic Control

Supporting countries to achieve and maintain epidemic control.

RISE enables countries to achieve PEPFAR targets and is a trusted partner in achieving HIV prevention, testing, and treatment targets. RISE kept HIV service delivery programs running throughout the COVID-19 health emergency, supporting countries to adapt HIV programming to allow for uninterrupted HIV/TB services for people at increased risk of HIV infection. RISE collaborates with countries to identify barriers, customize and adapt approaches, and institutionalize effective and efficient programming into health systems while keeping people at the center of the response. Continue reading.

Global Health Security

Capacity building to Prevent, Detect, and Respond to emerging health threats.

RISE works with country partners to prevent, contain, and respond to disease outbreaks, including Lassa Fever, Marburg, mpox, measles, influenza, and avian flu. RISE provides implementation and cross-cutting health systems strengthening support to address critical pandemic response priorities. This includes direct service delivery, technical assistance, and research where needed. Continue reading.

Mpox Capacity Statement

RISE assists countries to respond to the HIV, global health security, and mpox health emergencies, providing technical assistance, service delivery, research, and cross-cutting health systems support to address critical pandemic response priorities. The same technical capacities that have been brought to bear on HIV and COVID-19 are the exact capacities that we are adapting to the ongoing mpox outbreak. Continue reading.

Where RISE Works

RISE partners with ministries of health, local stakeholders, and nongovernmental organizations in more than 25 countries around the world. Continue reading.

RISE Achievements

RISE programming has addressed challenges in 26 countries

HIV response supported in 15 countries
COVID-19 response supported in 17 countries
COVID-19 test-to-treat programming in 5 countries
HIV technical assistance provided in 11 countries
Hosting HIV and/or HPV prevention research studies 2 countries
Read RISE by the Numbers.

Kishiwa Shiku posing with a VMMC brochure at his home place in Tabora region.

A Transformative Journey: Kishiwa Shiku’s Success Story of Health and Empowerment

For many years, Kishiwa Shiku, a resident of Tabora Region in Tanzania, firmly believed that male circumcision was a harmful practice that could lead to impotence and reduce a man’s sexual vitality.

Of the approximately 39.9 million people living with HIV, 1.3 million were newly infected in 2023. An estimated 5.4 million people did not know they were living with HIV in 2023.

— UNAIDS

The RISE provider toolkit is a vital resource to introduce CAB-LA to PrEP providers in PEPFAR-supported countries. It is designed to help clinicians learn about and support provision of CAB-LA as a new biomedical HIV prevention option.

Basic Emergency Care
Vaccines
Oxygen Infrastructure

Visit the RISE COVID-19 webpage for technical briefs, job aides and other resources created by RISE teams across the globe.

RISE advances HIV epidemic control through prevention, care and treatment. In December of 2022, 29.8 million people were accessing antiretroviral therapy, up from less than 8 million in 2010. New HIV infections have been reduced by 59%, and AIDS-related deaths reduced by 69% since their peak. RISE continues to contribute to this astounding legacy of progress.

RISE stands ready to support stakeholders to prepare for and remediate public health emergencies of international concern.

System-focused strategies that are responsive, holistic and flexible in the face of each country’s specific circumstances.

65% of countries lack a national public health emergency response plan for diseases with epidemic or pandemic potential.

RISE is funded with support from the United States Government, under the terms of the cooperative agreement 7200AA19CA00003. The contents are the responsibility of the RISE program and do not necessarily reflect the views of the United States Government.